/ writing
Writing.
Essays that take a position. Slower than blog posts, faster than papers.
- Stage × AI · Issue 1 of 38EssayHypothesis
Study Design: The Answer Is Chosen Before the Question Is Asked
Where AI helps at study design, where it must not go, and one buildable pattern: the design pre-mortem.
digital-twinsgovernance5 Under the Hoodlast tended 2026-07-26 - Stage × AI · Issue 2 of 38EssayHypothesis
Protocol Design: The Document That Runs the Trial
Where AI helps in clinical protocol design, where it must not go, and one buildable pattern: the citation-gated drafting loop.
raggovernance4 Under the Hoodlast tended 2026-07-19 - Stage × AI · Issue 33 of 38EssayHypothesis
Inspection: The Exam You've Been Taking All Along
Inspection readiness as retrieval engineering: where AI helps, where it must not go, and one buildable pattern — the always-on retrieval exam.
raggovernance5 Under the Hoodlast tended 2026-07-13 - Stage × AI · Issue 3 of 38EssayHypothesis
Feasibility: The Forecast Everyone Wants to Believe
Where AI helps in feasibility forecasting, where it must not go, and one buildable pattern: the calibrated forecast loop.
evaluationgovernance5 Under the Hoodlast tended 2026-07-13 - Stage × AI · Issue 5 of 38EssayHypothesis
Country Selection: The Same Protocol Asks Different Questions
Where AI helps at country selection, where it must not go, and one buildable pattern: the poolability loop.
knowledge-graphsgovernance5 Under the Hoodlast tended 2026-07-13 - Stage × AI · Issue 6 of 38EssayHypothesis
Site Selection: Paying for Zero
Where AI helps in site selection, where it must not go, and one buildable pattern: the site portfolio loop.
knowledge-graphsgovernance5 Under the Hoodlast tended 2026-07-13 - Stage × AI · Issue 4 of 38EssayHypothesis
Probability of Success: The Number That Moves the Money
Where AI helps at probability of success, where it must not go, and one buildable pattern: the scored portfolio.
evaluationgovernance5 Under the Hoodlast tended 2026-07-13 - Stage × AI · Issue 7 of 38EssayHypothesis
Study Startup: The Slowest Document Wins
Where AI helps at study startup, where it must not go, and one buildable pattern: the activation control tower.
agentsgovernance5 Under the Hoodlast tended 2026-07-13